Our Science
Microbiome and Cancer
Commensal microbes are found in tumor tissue itself, normal tissue adjacent to tumor and at tumor sites such as the gut, genitourinary tract and airway, with overlap between these sites. Microorganisms within, adjacent to and distant from the tumor may play a role in cancer development and progression, and interactions and differences between these microbial populations, with their associated molecules and molecular pathways, have the potential to
influence the course of disease
The microbiome of humans contains trillions of organisms distributed throughout the body. These organisms and their collective genomes – the human commensal microbiome – develops from birth, with influence from both the maternal microbiota and the environment, and varies between individuals due to the cumulative effects of host factors and environmental exposures
The human microbiome is an emerging target in cancer development and therapeutics. It may be directly oncogenic, through promotion of mucosal inflammation or systemic dysregulation, or may alter anticancer immunity/therapy.
Dysbiosis or disruption of the normal commensal microbiota is associated with a wide range of diseases, including inflammatory bowel disease, multiple sclerosis, obesity, autism, depression, cardiovascular disease and allergy, as well as cancer.
The microbiome has been implicated in cancer in a variety of specific ways, including being directly oncogenic, through promotion of oncogenic mucosal inflammation or systemic metabolic/immune dysregulation and through modulation of anti-cancer immunity or the efficacy of anti-cancer therapy
Designer microbiome
At CareBiom, we have developed specific strains and prebiotics technology using our BiomsifyTM Technology to create designer commensal with specific funcational characteristics
Microbiome Modulation
Our metagenomic-biomarker analysis, patented fermentation technology, and microbiome modulating synbiotic combinations allow us to modulate the commensal flora for enhancing cancer therapeutic efficacy and post treatment care programs
Microbiome Biobanking & metagenomics
Our microbiome analysis and storage services for cancer patients focused on novel insights on microbiome composition and metabolic profile that helps with cancer treatment and long-term care
Our Technology Platform
Our platform technologies are focused around analyzing and modulating commensal microflora and metabolic profile
Designer microbiome
At CareBiom, we have developed specific strains and prebiotics technology using our BiomsifyTM Technology to create designer commensal with specific funcational characteristics
Microbiome Modulation
Our metagenomic-biomarker analysis, patented fermentation technology, and microbiome modulating synbiotic combinations allow us to modulate the commensal flora for enhancing cancer therapeutic efficacy and post treatment care programs
Microbiome Biobanking & metagenomics
Our microbiome analysis and storage services for cancer patients focused on novel insights on microbiome composition and metabolic profile that helps with cancer treatment and long-term care
Our Technology Platform
Our platform technologies are focused around analyzing and modulating commensal microflora and metabolic profile